Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | HPGD | P15428 | 6/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.38 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CLK2 | P49760 | 1/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | ALB | P02768 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | AADAT | Q8N5Z0 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9703642 | 0.90 | KDM4E (0.47) | KDM4EALDH1A1HPGDHSD17B10POLB | |
| SCHEMBL9703371 | 0.87 | KDM4E (0.43) | KDM4EALDH1A1HPGDHSD17B10POLB | |
| Hydrochloric Acid SCHEMBL9703676 | 0.86 | KDM4E (0.42) | KDM4EALDH1A1HPGDHSD17B10POLB | |
| SCHEMBL9703873 | 0.85 | KDM4E (0.53) | KDM4EALDH1A1HPGDHSD17B10POLB | |
| SCHEMBL9703105 | 0.82 | KDM4E (0.51) | KDM4EALDH1A1HPGDHSD17B10POLB | |
| SCHEMBL9703722 | 0.78 | ADRB2 (0.39) | KDM4EALDH1A1HPGDHSD17B10POLB | |
| SCHEMBL9705566 | 0.78 | KDM4E (0.41) | KDM4EALDH1A1HPGDHSD17B10POLB | |
| SCHEMBL9703761 | 0.76 | KDM4E (0.52) | KDM4EALDH1A1HPGDHSD17B10POLB | |
| SCHEMBL9704563 | 0.76 | ALDH1A1 (0.42) | KDM4EALDH1A1HPGDHSD17B10POLB | |
| SCHEMBL9703898 | 0.75 | DYRK1A (0.41) | KDM4EALDH1A1HPGDHSD17B10POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0203795-B1 | Benzo [i,j] quinolizine-2-carboxylic acid derivatives, the salts and their hydrates, pharmaceutical compositions thereof, and process for preparing the same | TOKYO TANABE COMPANY LIMITED (JP) | 1992-07-29 | — | — | EP | disclosed |
| US-4720495-A | Benzo[ij]quinolizine-2-carboxylic acids useful for treating bacterial infection | TOKYO TANABE CO. LIMITED (JP) | 1988-01-19 | — | — | US | disclosed |
| EP-0203795-A2 | Benzo [i,j] quinolizine-2-carboxylic acid derivatives, the salts and their hydrates, pharmaceutical compositions thereof, and process for preparing the same | TOKYO TANABE COMPANY LIMITED (JP) | 1986-12-03 | — | — | EP | disclosed |