Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.56 |
| ▸ | EGFR | P00533 | 1/20 | 0.51 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | ACACB | O00763 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17211642 | 0.92 | ALDH1A1 (0.53) | NR1H4EGFRERBB2HIF1AEPAS1 | |
| SCHEMBL10453056 | 0.91 | KMT2A (0.60) | NR1H4EGFRERBB2HTTKMT2A | |
| SCHEMBL5582630 | 0.89 | MCHR1 (0.56) | NR1H4HTTKMT2AKDM4EMEN1 | |
| SCHEMBL5131798 | 0.88 | NR1H4 (0.47) | NR1H4EGFRERBB2HIF1AEPAS1 | |
| SCHEMBL9706241 | 0.83 | EGFR (0.58) | NR1H4EGFRERBB2HIF1AEPAS1 | |
| SCHEMBL18843564 | 0.82 | PPARG (0.39) | NR1H4HIF1AEPAS1ALDH1A1SMN1; SMN2 | |
| SCHEMBL505778 | 0.82 | ALDH1A1 (0.55) | NR1H4KMT2AKDM4EMEN1HSP90AA1 | |
| SCHEMBL9705583 | 0.82 | PPARG (0.39) | NR1H4HIF1AEPAS1ALDH1A1SMN1; SMN2 | |
| SCHEMBL25188378 | 0.80 | PPARG (0.42) | NR1H4EGFRERBB2KMT2AMEN1 | |
| SCHEMBL8953650 | 0.80 | SMN1; SMN2 (0.50) | HTTKMT2AALDH1A1SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0228803-B1 | IONENE ELASTOMERS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1992-09-16 | — | — | EP | disclosed |
| US-4794031-A | POLYMERIC DIAMINES, DIHALIDE LINKING AGENTS, POLYETHERS, ACRYLIC COPOLYMERS, ENCAPPING | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1988-12-27 | — | — | US | disclosed |
| US-4734458-A | QUATERNIZED POLYAMINES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1988-03-29 | — | — | US | disclosed |
| EP-0228803-A2 | Ionene elastomers | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1987-07-15 | — | — | EP | disclosed |
| US-4677182-A | COATINGS, ADHESIVES | MINNESOTA MINING AND MANUFACTURING CO. (US) | 1987-06-30 | — | — | US | disclosed |