SCHEMBL9705583

SCHEMBL9705583

CN(C(=O)N(C)c1ccc(CO)cc1)c1ccc(CO)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARG P37231 1/20 0.39
PPARA Q07869 1/20 0.39
NR1H4 Q96RI1 1/20 0.38
TSHR P16473 2/20 0.38
ALDH1A1 P00352 2/20 0.38
CYP3A4 P08684 1/20 0.38
MAPK1 P28482 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
ALOX15 P16050 1/20 0.38
CA1 P00915 3/20 0.38
CA2 P00918 3/20 0.38
CA12 O43570 1/20 0.38
CA4 P22748 1/20 0.38
CA6 P23280 1/20 0.38
CA5A P35218 1/20 0.38
CA7 P43166 1/20 0.38
CA9 Q16790 1/20 0.38
CA14 Q9ULX7 1/20 0.38
CA5B Q9Y2D0 1/20 0.38
HDAC1 Q13547 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18843564 1.00 PPARG (0.39) PPARGPPARANR1H4TSHRALDH1A1
SCHEMBL16601922 0.92 ALDH1A1 (0.44) TSHRALDH1A1ALOX15SMN1; SMN2MAPT
SCHEMBL7567915 0.92 MGLL (0.37) PPARGPPARANR1H4TSHRALDH1A1
SCHEMBL12550510 0.88 HSP90AA1 (0.49) PPARGPPARAALDH1A1SMN1; SMN2MAPT
SCHEMBL7563538 0.87 LMNA (0.43) PPARGPPARANR1H4TSHRALDH1A1
SCHEMBL25188378 0.85 PPARG (0.42) PPARGPPARANR1H4TSHRALDH1A1
SCHEMBL8953650 0.85 SMN1; SMN2 (0.50) ALDH1A1MAPK1ALOX15POLBSMN1; SMN2
SCHEMBL14053392 0.83 CYP4A11 (0.47) PPARATSHRTDP1ALOX15CA1
SCHEMBL20739091 0.82 KMT2A (0.37) PPARGPPARANR1H4TSHRALDH1A1
SCHEMBL9705548 0.82 NR1H4 (0.56) NR1H4ALDH1A1SMN1; SMN2HIF1AEPAS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9829810-B2 Electrophotographic photosensitive member, process cartridge, electrophotographic apparatus, and method for producing electrophotographic photosensitive member CANON KABUSHIKI KAISHA (JP) 2017-11-28 US disclosed
US-20170131646-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, ELECTROPHOTOGRAPHIC APPARATUS, AND METHOD FOR PRODUCING ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER CANON KABUSHIKI KAISHA (JP) 2017-05-11 US disclosed
EP-0228803-B1 IONENE ELASTOMERS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1992-09-16 EP disclosed
US-4794031-A POLYMERIC DIAMINES, DIHALIDE LINKING AGENTS, POLYETHERS, ACRYLIC COPOLYMERS, ENCAPPING MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1988-12-27 US disclosed
US-4734458-A QUATERNIZED POLYAMINES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1988-03-29 US disclosed
EP-0228803-A2 Ionene elastomers MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1987-07-15 EP disclosed
US-4677182-A COATINGS, ADHESIVES MINNESOTA MINING AND MANUFACTURING CO. (US) 1987-06-30 US disclosed