SCHEMBL17211642

SCHEMBL17211642

CN(C(=O)c1ccc(CO)cc1)c1ccc(Cl)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.53
SMN1; SMN2 Q16637 3/20 0.53
NR1H4 Q96RI1 1/20 0.50
EGFR P00533 1/20 0.49
ERBB2 P04626 1/20 0.49
HIF1A Q16665 1/20 0.46
EPAS1 Q99814 1/20 0.46
POLB P06746 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
CHEK2 O96017 1/20 0.44
PDK2 Q15119 1/20 0.44
PDK4 Q16654 1/20 0.44
MAPT P10636 3/20 0.43
HTT P42858 3/20 0.42
CNR1 P21554 1/20 0.42
GPBAR1 Q8TDU6 1/20 0.42
RAB9A P51151 3/20 0.41
L3MBTL1 Q9Y468 3/20 0.41
NPC1 O15118 2/20 0.41
KDM4E B2RXH2 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9705548 0.92 NR1H4 (0.56) ALDH1A1SMN1; SMN2NR1H4EGFRERBB2
SCHEMBL10453056 0.83 KMT2A (0.60) ALDH1A1SMN1; SMN2NR1H4EGFRERBB2
SCHEMBL23367841 0.81 SMN1; SMN2 (0.60) ALDH1A1SMN1; SMN2EGFRERBB2POLB
SCHEMBL5582630 0.81 MCHR1 (0.56) ALDH1A1SMN1; SMN2NR1H4POLBPDK2
SCHEMBL5131798 0.81 NR1H4 (0.47) ALDH1A1SMN1; SMN2NR1H4EGFRERBB2
SCHEMBL7400709 0.80 EGFR (0.48) ALDH1A1SMN1; SMN2NR1H4EGFRERBB2
SCHEMBL97673 0.80 EGFR (0.48) ALDH1A1SMN1; SMN2NR1H4EGFRERBB2
SCHEMBL7410067 0.80 CHEK2 (0.49) ALDH1A1SMN1; SMN2NR1H4EGFRERBB2
SCHEMBL1759738 0.80 ALDH1A1 (0.45) ALDH1A1SMN1; SMN2NR1H4EGFRERBB2
SCHEMBL1759739 0.80 ALDH1A1 (0.45) ALDH1A1SMN1; SMN2NR1H4EGFRERBB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9348177-B2 Optical film, optical compensation film, polarizing plate and liquid crystal display FUJIFILM CORPORATION (JP) 2016-05-24 US disclosed
US-20150309348-A1 OPTICAL FILM, OPTICAL COMPENSATION FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY FUJIFILM CORPORATION (JP) 2015-10-29 US disclosed