SCHEMBL9705638

SCHEMBL9705638

O=Cc1ccn(-c2c(Cl)cc(C(F)(F)F)cc2Cl)c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIA1 P42261 1/20 0.45
GRIA2 P42262 1/20 0.45
GRIA3 P42263 1/20 0.45
GRIA4 P48058 1/20 0.45
GABRA2 P47869 7/20 0.38
GABRB2 P47870 7/20 0.38
GABRB3 P28472 2/20 0.38
GABRP O00591 1/20 0.38
GABRD O14764 1/20 0.38
GABRA1 P14867 1/20 0.38
GABRB1 P18505 1/20 0.38
GABRG2 P18507 1/20 0.38
GABRA5 P31644 1/20 0.38
GABRA3 P34903 1/20 0.38
GABRA4 P48169 1/20 0.38
GABRE P78334 1/20 0.38
GABRA6 Q16445 1/20 0.38
GABRG1 Q8N1C3 1/20 0.38
GABRG3 Q99928 1/20 0.38
GABRQ Q9UN88 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1410369 0.80 GRIA1 (0.48) GRIA1GRIA2GRIA3GRIA4
SCHEMBL950782 0.77 ALDH1A1 (0.42) GRIA1GRIA2GRIA3GRIA4
SCHEMBL9774785 0.77 ALDH1A1 (0.35) GRIA1GRIA2GRIA3GRIA4GABRA2
SCHEMBL4118733 0.74 GRIA1 (0.46) GRIA1GRIA2GRIA3GRIA4
SCHEMBL18003321 0.74 GRIA1 (0.46) GRIA1GRIA2GRIA3GRIA4
SCHEMBL9704022 0.72 GABRB3 (0.41) GABRA2GABRB2GABRB3GABRPGABRD
SCHEMBL9218544 0.72 GABRA2 (0.59) GABRA2GABRB2GABRB3GABRPGABRD
SCHEMBL16402774 0.72 GRIA1 (0.60) GRIA1GRIA2GRIA3GRIA4
SCHEMBL18002705 0.71 GRIA1 (0.41) GRIA1GRIA2GRIA3GRIA4
SCHEMBL9704820 0.71 GAA (0.48) GABRA2GABRB2GABRB3GABRPGABRD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1992013451-A1 IMIDAZOLE PESTICIDES SCHERING AGROCHEMICALS LIMITED (GB) 1992-08-20 WO disclosed