SCHEMBL16402774

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL17802298	0.80	GRIA1 (0.57)	GRIA1GRIA2GRIA3GRIA4KIF11
	SCHEMBL4118733	0.76	GRIA1 (0.46)	GRIA1GRIA2GRIA3GRIA4CES2
	SCHEMBL1410369	0.75	GRIA1 (0.48)	GRIA1GRIA2GRIA3GRIA4CES2
	SCHEMBL8184247	0.74	GRIA1 (0.54)	GRIA1GRIA2GRIA3GRIA4KIF11
	SCHEMBL28876830	0.74	ALDH1A1 (0.62)	GRIA1GRIA2GRIA3GRIA4CES2
	SCHEMBL18003321	0.72	GRIA1 (0.46)	GRIA1GRIA2GRIA3GRIA4KIF11
	SCHEMBL9705638	0.72	GRIA1 (0.45)	GRIA1GRIA2GRIA3GRIA4
	SCHEMBL4922867	0.71	GRIA1 (0.44)	GRIA1GRIA2GRIA3GRIA4ALDH1A1
	SCHEMBL29935776	0.69	KIF11 (0.49)	GRIA1GRIA2GRIA3GRIA4KIF11
	SCHEMBL2749018	0.69	ALDH1A1 (0.40)	GRIA1GRIA2GRIA3GRIA4CES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.