Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 4/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | RARB | P10826 | 2/20 | 0.33 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | RARA | P10276 | 1/20 | 0.33 |
| ▸ | RARG | P13631 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | TPMT | P51580 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9200429 | 0.90 | PLAU (0.49) | NR1I2CYP3A4CYP2D6PLAUMRGPRX4 | |
| SCHEMBL9706268 | 0.86 | NR1I2 (0.45) | NR1I2CYP3A4CYP2D6PLAUMRGPRX4 | |
| SCHEMBL10413141 | 0.85 | PLAU (0.51) | NR1I2CYP3A4CYP2D6PLAUHDAC6 | |
| SCHEMBL9706270 | 0.85 | KDM4E (0.42) | NR1I2CYP3A4CYP2D6PLAUHDAC6 | |
| SCHEMBL9705949 | 0.81 | TPMT (0.39) | NR1I2CYP3A4CYP2D6PLAUTPMT | |
| SCHEMBL9705668 | 0.81 | NR1I2 (0.45) | NR1I2CYP3A4CYP2D6 | |
| SCHEMBL9862923 | 0.81 | NR1I2 (0.45) | NR1I2CYP3A4CYP2D6PLAURARB | |
| SCHEMBL9436198 | 0.80 | LMNA (0.42) | NR1I2CYP3A4CYP2D6PLAUHDAC6 | |
| SCHEMBL9705669 | 0.79 | CYP2D6 (0.41) | NR1I2CYP3A4CYP2D6PLAUMRGPRX4 | |
| SCHEMBL9863245 | 0.78 | POLB (0.45) | NR1I2CYP3A4CYP2D6TPMTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0207454-B1 | ISOXAZOLE AND FURAN DERIVATIVES, THEIR PREPARATION AND USE AS ANTIVIRAL AGENTS | STERLING WINTHROP INC. (US) | 1992-09-09 | — | — | EP | disclosed |
| US-5002960-A | Viricides for combating picornaviruses | STERLING DRUG, INC. (US) | 1991-03-26 | — | — | US | disclosed |
| US-4939267-A | Viricides | STERLING DRUG INC. (US) | 1990-07-03 | — | — | US | disclosed |
| US-4843087-A | OXAZOLINYL COMPOUNDS; RHINOVIRUSES AND PICORNAVIRUSES | STERLING DRUG INC. (US) | 1989-06-27 | — | — | US | disclosed |
| EP-0207454-A2 | Isoxazole and furan derivatives, their preparation and use as antiviral agents | STERLING WINTHROP INC. (US) | 1987-01-07 | — | — | EP | disclosed |