Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CMA1 | P23946 | 1/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5545709 | 0.92 | CMA1 (0.56) | CMA1SIGMAR1PKMKMT2AMEN1 | |
| SCHEMBL9705989 | 0.83 | GAA (0.52) | CMA1SIGMAR1KMT2AMEN1ALDH1A1 | |
| SCHEMBL9705894 | 0.80 | BCL2L1 (0.39) | SIGMAR1KMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL8799862 | 0.78 | KMT2A (0.60) | CMA1SIGMAR1PKMKMT2AMEN1 | |
| SCHEMBL5982177 | 0.78 | L3MBTL1 (0.54) | CMA1SIGMAR1KMT2AMEN1ALDH1A1 | |
| SCHEMBL5537205 | 0.77 | ROCK2 (0.42) | CMA1PKMKMT2AMEN1GAA | |
| SCHEMBL26357193 | 0.77 | KMT2A (0.58) | CMA1SIGMAR1PKMKMT2AMEN1 | |
| SCHEMBL3120489 | 0.76 | CMA1 (0.54) | CMA1SIGMAR1PKMKMT2AMEN1 | |
| SCHEMBL4004474 | 0.75 | MEN1 (0.67) | CMA1SIGMAR1PKMKMT2AMEN1 | |
| SCHEMBL30527306 | 0.75 | MEN1 (0.67) | CMA1SIGMAR1PKMKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0470543-A1 | Heterocyclic imidazoles, remedies containing them and processes for their preparation | Dr. Karl Thomae GmbH (DE) | 1992-02-12 | — | — | EP | disclosed |