Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.64 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.64 |
| ▸ | ALB | P02768 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | TK1 | P04183 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | DTYMK | P23919 | 1/20 | 0.41 |
| ▸ | TK2 | O00142 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19493129 | 1.00 | LMNA (0.64) | LMNASMN1; SMN2ALOX12ADRA1AALB | |
| SCHEMBL2041288 | 1.00 | LMNA (0.64) | LMNASMN1; SMN2ALOX12ADRA1AALB | |
| SCHEMBL21277491 | 0.90 | LMNA (0.58) | LMNASMN1; SMN2ALOX12ADRA1AALB | |
| SCHEMBL3437129 | 0.83 | LMNA (0.62) | LMNASMN1; SMN2ALOX12ADRA1AALB | |
| SCHEMBL21345305 | 0.83 | LMNA (0.62) | LMNASMN1; SMN2ALOX12ADRA1AALB | |
| SCHEMBL26296051 | 0.83 | LMNA (0.62) | LMNASMN1; SMN2ALOX12ADRA1AALB | |
| SCHEMBL3437131 | 0.83 | LMNA (0.62) | LMNASMN1; SMN2ALOX12ADRA1AALB | |
| SCHEMBL8104286 | 0.83 | LMNA (0.62) | LMNASMN1; SMN2ALOX12ADRA1AALB | |
| SCHEMBL9706045 | 0.83 | LMNA (0.53) | LMNASMN1; SMN2ALOX12ADRA1ATK1 | |
| SCHEMBL19657129 | 0.82 | LMNA (0.48) | LMNASMN1; SMN2ALOX12ADRA1AALB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0507188-A1 | Substituted 2',3'-dideoxy-5-trifluoromethyluridines, method of their preparation and their use in medicaments | BAYER AG (DE) | 1992-10-07 | — | — | EP | disclosed |
| EP-0507188-A1 | Substituted 2',3'-dideoxy-5-trifluoromethyluridines, method of their preparation and their use in medicaments | BAYER AG (DE) | 1992-10-07 | — | — | EP | disclosed |
| US-5064946-A | 3-azido-2,3-dideoxy-B-D-erythro-pentofuranosyl derivatives of 4(1H)-pyrimidinones; antiretroviral, anti-AIDS | BURROUGHS WELLCOME CO. (US) | 1991-11-12 | — | — | US | disclosed |
| EP-0217580-A2 | Therapeutic nucleosides | THE WELLCOME FOUNDATION LIMITED (GB) | 1987-04-08 | — | — | EP | disclosed |