SCHEMBL19664384

SCHEMBL19664384

CCOC(=O)Oc1ccnc(OC(=O)OCC)c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.45
CA2 P00918 1/20 0.43
MEN1 O00255 3/20 0.42
POLB P06746 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
MAPT P10636 2/20 0.38
KDM4E B2RXH2 2/20 0.38
LMNA P02545 1/20 0.38
ALDH1A1 P00352 1/20 0.38
CYP1A2 P05177 1/20 0.38
NOS1 P29475 2/20 0.37
NOS2 P35228 2/20 0.37
MMP2 P08253 1/20 0.36
MMP9 P14780 1/20 0.36
MMP8 P22894 1/20 0.36
MMP14 P50281 1/20 0.36
NOS3 P29474 1/20 0.36
CRHBP P24387 1/20 0.36
CRHR2 Q13324 1/20 0.36
JMJD6 Q6NYC1 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9199729 0.87 ALDH1A1 (0.38) KMT2ACA2MEN1POLBL3MBTL1
SCHEMBL9196824 0.84 L3MBTL1 (0.38) KMT2ACA2MEN1POLBL3MBTL1
SCHEMBL19664382 0.84 TDP1 (0.36) KMT2ACA2MEN1POLBL3MBTL1
SCHEMBL9663046 0.83 TSHR (0.38) KMT2AMAPTKDM4ELMNANOS2
SCHEMBL9326916 0.83 KMT2A (0.44) KMT2ACA2MEN1POLBL3MBTL1
SCHEMBL9662430 0.82 LMNA (0.36) KMT2APOLBMAPTLMNAALDH1A1
SCHEMBL9568958 0.81 AAK1 (0.38) KMT2AMEN1KDM4EALDH1A1NOS1
SCHEMBL10672147 0.81 RECQL (0.41) KMT2ACA2ALDH1A1JMJD6NUDT1
SCHEMBL30596392 0.80 CCR1 (0.59) KMT2ACA2MEN1POLBL3MBTL1
SCHEMBL7409103 0.79 HCRTR2 (0.46) KMT2AMEN1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2861206-B1 COMPOSITION INCLUDING A PYRIDINE DICARBOXYLIC ACID ESTER AND A BINDING POLYMER, METHOD THEREFOR, AND USE THEREOF FOR TREATING HAIR OREAL (FR) 2019-06-12 EP claimed
EP-2861205-B1 COMPOSITION INCLUDING A PYRIDINE DICARBOXYLIC ACID ESTER AND A GLUCOSE AND FATTY ACID ESTER. OREAL (FR) 2017-12-06 EP claimed