Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 4/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | TK2 | O00142 | 10/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9706119 | 0.90 | TK1 (0.61) | TK1CYP1A2CYP3A4TSHRBLM | |
| SCHEMBL9706162 | 0.89 | TK1 (0.56) | TK1CYP1A2CYP3A4TSHRBLM | |
| SCHEMBL9309692 | 0.86 | TK1 (0.76) | TK1CYP1A2CYP3A4TSHRBLM | |
| SCHEMBL8798117 | 0.85 | TK1 (0.67) | TK1CYP1A2CYP3A4TSHRBLM | |
| SCHEMBL8689486 | 0.85 | TK1 (0.67) | TK1CYP1A2CYP3A4TSHRBLM | |
| SCHEMBL9481617 | 0.85 | TK1 (0.67) | TK1CYP1A2CYP3A4TSHRBLM | |
| SCHEMBL9706089 | 0.81 | TK1 (0.51) | TK1BLMTK2 | |
| SCHEMBL9308662 | 0.81 | TK1 (0.88) | TK1CYP1A2CYP3A4TSHRBLM | |
| SCHEMBL9706090 | 0.80 | LMNA (0.49) | TK1TSHRPMP22 | |
| SCHEMBL9309162 | 0.79 | TK1 (0.63) | TK1CYP1A2CYP3A4TSHRBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0481320-A1 | Novel cyclobutane derivatives | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1992-04-22 | — | — | EP | disclosed |