Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 2/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | DHFR | P00374 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 2/20 | 0.34 |
| ▸ | CASP7 | P55210 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.34 |
| ▸ | AHR | P35869 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9706081 | 0.77 | MAPT (0.38) | MAPK1ALOX15MAPTTSHRLMNA | |
| SCHEMBL9706257 | 0.77 | ALOX15 (0.80) | MAPK1ALOX15MAPTTSHRLMNA | |
| SCHEMBL9706113 | 0.76 | MAPK1 (0.37) | MAPK1ALOX15MAPTTSHRLMNA | |
| SCHEMBL9706123 | 0.68 | MAPT (0.47) | MAPK1ALOX15MAPTTSHRLMNA | |
| SCHEMBL9706152 | 0.68 | MEN1 (0.45) | MAPK1ALOX15MAPTTSHRLMNA | |
| SCHEMBL9706117 | 0.67 | MAPK1 (0.47) | MAPK1ALOX15MAPTTSHRLMNA | |
| SCHEMBL9706132 | 0.66 | MAPT (0.51) | MAPK1ALOX15MAPTTSHRATM | |
| Dimethylamine SCHEMBL9706094 | 0.66 | MAPT (0.51) | MAPK1ALOX15MAPTTSHRLMNA | |
| SCHEMBL9436917 | 0.65 | KDM4E (0.54) | MAPK1ALOX15MAPTTSHRLMNA | |
| SCHEMBL9706088 | 0.65 | MAPK1 (0.50) | MAPK1ALOX15MAPTTSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0238459-B1 | SUBSTITUTED INDOLOQUINOXALINES | Lundblad, Leif (SE) | 1992-04-15 | — | — | EP | disclosed |
| US-4990510-A | Viricides, anticancer agents | LEIF LUNDBLAD (BE) | 1991-02-05 | — | — | US | disclosed |
| EP-0238459-A1 | Substituted indoloquinoxalines | Lundblad, Leif (SE) | 1987-09-23 | — | — | EP | disclosed |
| WO-1987004436-A1 | SUBSTITUTED INDOLOQUINOXALINES | LUNDBLAD, LEIF (SE) | 1987-07-30 | — | — | WO | disclosed |