Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 20/20 | 0.80 |
| ▸ | CTSD | P07339 | 2/20 | 0.80 |
| ▸ | CTSE | P14091 | 2/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9706379 | 0.84 | REN (0.58) | RENCTSDCTSE | |
| SCHEMBL7361383 | 0.81 | REN (0.63) | RENCTSDCTSE | |
| SCHEMBL9513094 | 0.80 | REN (0.62) | RENCTSDCTSE | |
| SCHEMBL29624125 | 0.79 | REN (0.81) | RENCTSDCTSE | |
| SCHEMBL15532120 | 0.79 | REN (0.81) | RENCTSDCTSE | |
| SCHEMBL9512616 | 0.79 | REN (0.61) | RENCTSDCTSE | |
| SCHEMBL10448148 | 0.77 | REN (0.74) | RENCTSDCTSE | |
| SCHEMBL7274657 | 0.77 | REN (0.60) | RENCTSDCTSE | |
| SCHEMBL30747203 | 0.74 | REN (0.72) | REN | |
| SCHEMBL8238484 | 0.74 | REN (0.55) | RENCTSDCTSE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992010509-A1 | RENIN-INHIBITING PEPTIDES OF THE CYCLOHEXYLSTATIN TYPE, PROCESS FOR PRODUCING THE SAME AND THEIR USE IN MEDICAMENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1992-06-25 | — | — | WO | disclosed |
| EP-0403828-A1 | Renin-inhibiting peptides, their preparation and their use in medicaments | BAYER AG (DE) | 1990-12-27 | — | — | EP | disclosed |