Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 19/20 | 0.63 |
| ▸ | CTSD | P07339 | 1/20 | 0.63 |
| ▸ | CTSE | P14091 | 1/20 | 0.63 |
| ▸ | PGA5 | P0DJD9 | 1/20 | 0.55 |
| ▸ | CTSS | P25774 | 1/20 | 0.55 |
| ▸ | CTSK | P43235 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7362226 | 0.90 | ALDH1A1 (0.62) | RENCTSDCTSECTSSCTSK | |
| SCHEMBL9130011 | 0.89 | CA2 (0.59) | RENCTSDCTSEPGA5CTSS | |
| SCHEMBL9130009 | 0.89 | CA2 (0.59) | RENCTSDCTSEPGA5CTSS | |
| SCHEMBL8549092 | 0.83 | CTSS (0.64) | CTSSCTSK | |
| SCHEMBL8549086 | 0.83 | CTSS (0.64) | CTSSCTSK | |
| SCHEMBL7954670 | 0.82 | SMN1; SMN2 (0.50) | RENCTSDCTSECTSK | |
| SCHEMBL10520400 | 0.82 | REN (0.47) | RENCTSDCTSEPGA5CTSS | |
| SCHEMBL9706320 | 0.81 | REN (0.80) | RENCTSDCTSE | |
| SCHEMBL7366909 | 0.81 | SMN1; SMN2 (0.49) | RENCTSDCTSECTSSCTSK | |
| SCHEMBL10799756 | 0.80 | KDM4E (0.51) | RENCTSDCTSECTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0602306-A1 | Retroviral protease inhibitors | AMERICAN CYANAMID COMPANY (US) | 1994-06-22 | — | — | EP | disclosed |
| EP-0578745-A1 | PHOSPHORUS CONTAINING COMPOUNDS AS INHIBITORS OF RETROVIRUSES | THE UPJOHN COMPANY (US) | 1994-01-19 | — | — | EP | disclosed |
| WO-1992017490-A1 | PHOSPHORUS CONTAINING COMPOUNDS AS INHIBITORS OF RETROVIRUSES | THE UPJOHN COMPANY (US) | 1992-10-15 | — | — | WO | disclosed |
| WO-1992010509-A1 | RENIN-INHIBITING PEPTIDES OF THE CYCLOHEXYLSTATIN TYPE, PROCESS FOR PRODUCING THE SAME AND THEIR USE IN MEDICAMENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1992-06-25 | — | — | WO | disclosed |
| EP-0403828-A1 | Renin-inhibiting peptides, their preparation and their use in medicaments | BAYER AG (DE) | 1990-12-27 | — | — | EP | disclosed |