Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.65 |
| ▸ | LMNA | P02545 | 4/20 | 0.65 |
| ▸ | MAOA | P21397 | 3/20 | 0.59 |
| ▸ | MAOB | P27338 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | NPC1 | O15118 | 3/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 5/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | GFER | P55789 | 1/20 | 0.55 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.55 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9371126 | 0.90 | RAB9A (0.64) | RAB9ALMNAMAOAMAOBMEN1 | |
| SCHEMBL9370565 | 0.90 | RAB9A (0.58) | RAB9ALMNAMAOAMAOBMEN1 | |
| SCHEMBL9370682 | 0.89 | LMNA (0.72) | RAB9ALMNAMEN1KMT2ANPC1 | |
| SCHEMBL9371423 | 0.89 | RAB9A (0.66) | RAB9ALMNAMAOAMAOBMEN1 | |
| SCHEMBL9371376 | 0.87 | KMT2A (0.64) | RAB9AMAOAMAOBMEN1KMT2A | |
| SCHEMBL9370811 | 0.85 | ROCK1 (0.55) | RAB9ALMNAMAOAMAOBMEN1 | |
| SCHEMBL9371125 | 0.84 | ROCK1 (0.63) | RAB9ALMNAMEN1KMT2APOLB | |
| SCHEMBL9373833 | 0.84 | MAPT (0.67) | RAB9ALMNAMEN1KMT2ANPC1 | |
| SCHEMBL9370967 | 0.83 | ABL1 (0.62) | RAB9ALMNAMAOAMAOBMEN1 | |
| SCHEMBL9370348 | 0.83 | LMNA (0.61) | RAB9ALMNAMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0519449-A1 | 2-Amino-4-aryl thiazoles with antiasthmatic and antiinflammatory activities on the respiratory tract | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1992-12-23 | — | — | EP | disclosed |