SCHEMBL9706650

SCHEMBL9706650

CCc1c(C)c(=O)n(-c2cc(C(=O)O)c(Cl)cc2F)c(=O)n1C

nearest known ligand 0.34

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
NOTUM Q6P988 5/20 0.34
BRD9 Q9H8M2 1/20 0.33
MYC P01106 2/20 0.33
NR4A1 P22736 2/20 0.33
CTSB P07858 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
CMA1 P23946 1/20 0.32
GRM4 Q14833 2/20 0.31
BAZ2B Q9UIF8 1/20 0.31
BAZ2A Q9UIF9 1/20 0.31
FPR2 P25090 1/20 0.31
DRD3 P35462 1/20 0.31
HPGD P15428 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
TSHR P16473 1/20 0.31
RORC P51449 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9706659 0.86 NOTUM (0.39) NOTUMMYCNR4A1CTSBTDP1
SCHEMBL9706615 0.85 LMNA (0.34) BAZ2BBAZ2AHPGDSMN1; SMN2
SCHEMBL9706646 0.83 NOTUM (0.37) NOTUMBRD9MYCNR4A1CTSB
SCHEMBL9706662 0.82 NOTUM (0.40) NOTUMMYCNR4A1CTSBTDP1
SCHEMBL9706512 0.81 NOTUM (0.41) NOTUMMYCNR4A1CTSBTDP1
SCHEMBL24151268 0.80 NOTUM (0.38) NOTUMMYCNR4A1CTSBTDP1
SCHEMBL29938165 0.80 NOTUM (0.38) NOTUMMYCNR4A1CTSBTDP1
SCHEMBL9706626 0.80 NOTUM (0.36) NOTUMMYCNR4A1CTSBTDP1
SCHEMBL9706621 0.80 NOTUM (0.36) NOTUMMYCNR4A1CTSBTDP1
SCHEMBL9706620 0.79 BRD9 (0.34) NOTUMBRD9MYCNR4A1CTSB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0195346-B1 3-ARYL URACILES AND THEIR USE AS HERBICIDES CIBA-GEIGY AG (CH) 1992-06-24 EP claimed