Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9706651 | 0.91 | PPOX (0.34) | SLC6A2SLC6A3HPGDLMNASMN1; SMN2 | |
| SCHEMBL9706485 | 0.91 | SLC6A2 (0.34) | SLC6A2SLC6A3 | |
| SCHEMBL9469456 | 0.89 | SLC6A2 (0.33) | SLC6A2SLC6A3HPGDKDM4E | |
| SCHEMBL9706675 | 0.89 | PPOX (0.36) | SLC6A2SLC6A3HPGDLMNASMN1; SMN2 | |
| SCHEMBL9706680 | 0.85 | LMNA (0.37) | ALDH1A1LMNATSHRMEN1KMT2A | |
| SCHEMBL10647260 | 0.84 | SLC6A2 (0.39) | SLC6A2SLC6A3HPGDALDH1A1POLB | |
| SCHEMBL10645208 | 0.83 | KDM4E (0.30) | HPGDALDH1A1KDM4EHSD17B10 | |
| SCHEMBL10649662 | 0.83 | OPRK1 (0.33) | HPGDALDH1A1KDM4EHSD17B10 | |
| SCHEMBL9706603 | 0.82 | SLC6A2 (0.37) | SLC6A2SLC6A3HPGDALDH1A1POLB | |
| SCHEMBL9706594 | 0.81 | OPRK1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0195346-B1 | 3-ARYL URACILES AND THEIR USE AS HERBICIDES | CIBA-GEIGY AG (CH) | 1992-06-24 | — | — | EP | claimed |
| US-4760163-A | 3-(5-carboxy-4-substituted-phenyl)-(thio)uracil-esters and salts | HOFFMANN-LAROCHE INC. (US) | 1988-07-26 | — | — | US | disclosed |
| US-4746352-A | HERBICIDES | HOFFMANN-LA ROCHE INC. (US) | 1988-05-24 | — | — | US | disclosed |