SCHEMBL9706680

SCHEMBL9706680

Cn1c2c(c(=O)n(-c3cc(C(=O)O)c(Cl)cc3Cl)c1=O)CCC2

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.37
MEN1 O00255 1/20 0.37
ALDH1A1 P00352 1/20 0.37
KMT2A Q03164 1/20 0.37
CMA1 P23946 2/20 0.35
RXFP1 Q9HBX9 1/20 0.33
GAA P10253 1/20 0.32
TSHR P16473 1/20 0.32
NOTUM Q6P988 2/20 0.32
MYC P01106 1/20 0.32
NR4A1 P22736 1/20 0.32
CTSB P07858 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
HSP90AA1 P07900 1/20 0.31
GRM4 Q14833 4/20 0.31
FABP4 P15090 2/20 0.31
CA12 O43570 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA3 P07451 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9706678 0.90 CMA1 (0.34) CMA1RXFP1GAANOTUMGRM4
SCHEMBL9706554 0.90 HPGD (0.34) LMNAMEN1ALDH1A1KMT2ACMA1
SCHEMBL10645585 0.89 HPGD (0.34) LMNAMEN1ALDH1A1KMT2ACMA1
SCHEMBL9706687 0.87 HPGD (0.34) LMNAMEN1ALDH1A1KMT2ACMA1
SCHEMBL9706672 0.85 SLC6A2 (0.35) LMNAMEN1ALDH1A1KMT2ATSHR
SCHEMBL9706570 0.82 TDP1 (0.50) LMNAMEN1ALDH1A1KMT2ACMA1
SCHEMBL10873317 0.81 RXRA (0.34) LMNAMEN1KMT2ACMA1RXFP1
SCHEMBL9423141 0.81 TSHR (0.36) ALDH1A1RXFP1TSHRHSP90AA1
SCHEMBL9706652 0.80 TDP1 (0.50) LMNAMEN1ALDH1A1KMT2ACMA1
SCHEMBL10649882 0.79 TDP1 (0.49) LMNAMEN1ALDH1A1KMT2ACMA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0195346-B1 3-ARYL URACILES AND THEIR USE AS HERBICIDES CIBA-GEIGY AG (CH) 1992-06-24 EP claimed