Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.33 |
| ▸ | WDR5 | P61964 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | PPOX | P50336 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10644831 | 0.85 | BCAT2 (0.33) | MAPTLMNAHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL9706614 | 0.84 | SLC9A1 (0.37) | MAPTSLC9A1 | |
| SCHEMBL9706686 | 0.83 | ALDH1A1 (0.35) | MAPTLMNAHPGDSMN1; SMN2WDR5 | |
| SCHEMBL9706535 | 0.83 | ALDH1A1 (0.35) | MAPTLMNAHPGDSMN1; SMN2WDR5 | |
| SCHEMBL10644543 | 0.83 | ALDH1A1 (0.34) | MAPTLMNAHPGDSMN1; SMN2WDR5 | |
| SCHEMBL10645636 | 0.82 | ALDH1A1 (0.34) | MAPTLMNAHPGDSMN1; SMN2WDR5 | |
| SCHEMBL9879094 | 0.81 | LMNA (0.35) | MAPTLMNAHPGDSMN1; SMN2WDR5 | |
| SCHEMBL10647527 | 0.81 | BAZ2B (0.35) | MAPTLMNAHPGDSMN1; SMN2WDR5 | |
| SCHEMBL9706706 | 0.81 | MAPT (0.33) | MAPTLMNAHPGDSMN1; SMN2WDR5 | |
| SCHEMBL10645460 | 0.79 | MAPT (0.34) | MAPTLMNAHPGDSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0195346-B1 | 3-ARYL URACILES AND THEIR USE AS HERBICIDES | CIBA-GEIGY AG (CH) | 1992-06-24 | — | — | EP | claimed |
| US-4760163-A | 3-(5-carboxy-4-substituted-phenyl)-(thio)uracil-esters and salts | HOFFMANN-LAROCHE INC. (US) | 1988-07-26 | — | — | US | disclosed |
| US-4746352-A | HERBICIDES | HOFFMANN-LA ROCHE INC. (US) | 1988-05-24 | — | — | US | disclosed |