Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 1/20 | 0.72 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.72 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9706771 | 0.85 | ADRA1A (0.74) | ADRA1APDE4DGAASMN1; SMN2 | |
| Malotilate SCHEMBL635496 | 0.84 | ADRA1A (1.00) | ADRA1APDE4DGAASMN1; SMN2KMT2A | |
| SCHEMBL9675247 | 0.81 | ADRA1A (0.62) | ADRA1APDE4DSMN1; SMN2TSHR | |
| SCHEMBL8055886 | 0.80 | ADRA1A (0.82) | ADRA1APDE4DGAASMN1; SMN2KMT2A | |
| SCHEMBL9706734 | 0.78 | ADRA1A (0.79) | ADRA1APDE4DGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL9672860 | 0.78 | ADRA1A (0.62) | ADRA1APDE4DGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL9706769 | 0.77 | ADRA1A (0.60) | ADRA1APDE4DGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL9673501 | 0.77 | ADRA1A (0.60) | ADRA1APDE4DGAASMN1; SMN2NLRP3 | |
| SCHEMBL9675401 | 0.77 | ADRA1A (0.60) | ADRA1APDE4DSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL9674389 | 0.77 | ADRA1A (0.60) | ADRA1APDE4DGAASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5158950-A | Treatment of liver disorders | YUHAN CORPORATION, LTD. (KR) | 1992-10-27 | — | — | US | disclosed |