Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 1/20 | 0.68 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Malotilate SCHEMBL635496 | 0.82 | ADRA1A (1.00) | ADRA1APDE4DHPGDMEN1KMT2A | |
| SCHEMBL8050522 | 0.78 | ADRA1A (0.77) | ADRA1APDE4DALDH1A1MEN1KMT2A | |
| SCHEMBL8055886 | 0.77 | ADRA1A (0.82) | ADRA1APDE4DMEN1KMT2A | |
| SCHEMBL9672633 | 0.76 | ADRA1A (0.63) | ADRA1APDE4D | |
| SCHEMBL9706734 | 0.76 | ADRA1A (0.79) | ADRA1APDE4DALDH1A1 | |
| SCHEMBL9706755 | 0.74 | ADRA1A (0.60) | ADRA1APDE4DMEN1KMT2A | |
| SCHEMBL9674608 | 0.74 | ADRA1A (0.69) | ADRA1APDE4DALDH1A1 | |
| SCHEMBL9706771 | 0.73 | ADRA1A (0.74) | ADRA1APDE4D | |
| SCHEMBL9675124 | 0.72 | ADRA1A (0.68) | ADRA1APDE4DTP53 | |
| SCHEMBL9706732 | 0.72 | ADRA1A (0.72) | ADRA1APDE4DALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5158950-A | Treatment of liver disorders | YUHAN CORPORATION, LTD. (KR) | 1992-10-27 | — | — | US | disclosed |
| EP-0298040-A1 | 1,3-Dithiol-2-ylidene derivatives | YUHAN CORPORATION, LTD. (KR) | 1989-01-04 | — | — | EP | disclosed |