Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NSD2 | O96028 | 2/20 | 0.34 |
| ▸ | PARG | Q86W56 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | ACP1 | P24666 | 2/20 | 0.31 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1726899 | 0.91 | — | — | |
| Ammonia Solution, Strong SCHEMBL4593126 | 0.88 | MAPT (0.31) | SMN1; SMN2MAPTKDM4EMEN1NPC1 | |
| SCHEMBL27847630 | 0.88 | MAPT (0.31) | SMN1; SMN2MAPTKDM4EMEN1NPC1 | |
| Diethylamine SCHEMBL16433288 | 0.77 | LMNA (0.39) | MEN1LMNAHPGDKMT2A | |
| Benzene SCHEMBL3694132 | 0.72 | NSD2 (0.38) | SMN1; SMN2MAPTKDM4EMEN1NPC1 | |
| Benzene SCHEMBL28337255 | 0.71 | CA2 (0.47) | SMN1; SMN2MAPTKDM4EMEN1LMNA | |
| Benzene SCHEMBL4447245 | 0.71 | CA2 (0.47) | SMN1; SMN2MAPTKDM4EMEN1LMNA | |
| SCHEMBL28304615 | 0.71 | — | — | |
| SCHEMBL9987191 | 0.69 | ALDH1A1 (0.41) | ALDH1A1TSHR | |
| Benzene SCHEMBL28043681 | 0.68 | CA2 (0.44) | SMN1; SMN2MAPTKDM4ELMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0511073-A1 | Antiserotonines, their preparation and medicaments containing them | Aventis Pharma S.A. (FR) | 1992-10-28 | — | — | EP | disclosed |