SCHEMBL9707042

SCHEMBL9707042

C[C@@H](Cc1ccc(O)cc1)NS(=O)(=O)c1ccc(Cl)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR3C1 P04150 1/20 0.51
KMT2A Q03164 3/20 0.50
MEN1 O00255 2/20 0.50
L3MBTL1 Q9Y468 2/20 0.50
HDAC3 O15379 1/20 0.49
HDAC4 P56524 1/20 0.49
HDAC1 Q13547 1/20 0.49
HDAC7 Q8WUI4 1/20 0.49
HDAC2 Q92769 1/20 0.49
HDAC10 Q969S8 1/20 0.49
HDAC11 Q96DB2 1/20 0.49
HDAC8 Q9BY41 1/20 0.49
HDAC6 Q9UBN7 1/20 0.49
HDAC9 Q9UKV0 1/20 0.49
HDAC5 Q9UQL6 1/20 0.49
MMP2 P08253 5/20 0.49
ADAMTS5 Q9UNA0 1/20 0.49
NPSR1 Q6W5P4 1/20 0.49
ALDH1A1 P00352 2/20 0.47
MMP1 P03956 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9513690 1.00 NR3C1 (0.51) NR3C1KMT2AMEN1L3MBTL1HDAC3
SCHEMBL9707055 0.87 CA2 (0.57) NR3C1KMT2AMEN1L3MBTL1MMP2
SCHEMBL9765313 0.87 NR3C1 (0.52) NR3C1KMT2AHDAC3HDAC4HDAC1
SCHEMBL9707060 0.87 CA2 (0.57) NR3C1KMT2AMEN1L3MBTL1MMP2
SCHEMBL10448359 0.86 NR3C1 (0.51) NR3C1KMT2AMEN1HDAC3HDAC4
SCHEMBL9707094 0.85 ALDH1A1 (0.57) KMT2AMEN1L3MBTL1HDAC1MMP2
SCHEMBL9765320 0.85 ALDH1A1 (0.57) KMT2AMEN1L3MBTL1HDAC1MMP2
SCHEMBL9707087 0.85 ALDH1A1 (0.57) KMT2AMEN1L3MBTL1HDAC1MMP2
SCHEMBL9765250 0.83 ALDH1A1 (0.57) MMP2ALDH1A1MMP1MMP3MMP7
SCHEMBL10476890 0.83 EGFR (0.51) NR3C1HDAC3HDAC4HDAC1HDAC7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0502498-A1 Phenoxyalkanoic acid derivatives and process for preparation thereof TANABE SEIYAKU CO., LTD. (JP) 1992-09-09 EP disclosed