Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | MMP2 | P08253 | 5/20 | 0.47 |
| ▸ | MMP9 | P14780 | 4/20 | 0.47 |
| ▸ | ADAMTS4 | O75173 | 2/20 | 0.47 |
| ▸ | MMP7 | P09237 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
| ▸ | MMP14 | P50281 | 1/20 | 0.46 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9765320 | 1.00 | ALDH1A1 (0.57) | ALDH1A1CYP1A2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL9707094 | 1.00 | ALDH1A1 (0.57) | ALDH1A1CYP1A2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL27284050 | 0.89 | ALDH1A1 (0.71) | ALDH1A1CYP1A2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL9707055 | 0.87 | CA2 (0.57) | ALDH1A1MEN1KMT2AL3MBTL1NPSR1 | |
| SCHEMBL9707060 | 0.87 | CA2 (0.57) | ALDH1A1MEN1KMT2AL3MBTL1NPSR1 | |
| SCHEMBL9707042 | 0.85 | NR3C1 (0.51) | ALDH1A1CYP1A2CYP2C9CYP2C19MEN1 | |
| SCHEMBL9513690 | 0.85 | NR3C1 (0.51) | ALDH1A1CYP1A2CYP2C9CYP2C19MEN1 | |
| SCHEMBL9765250 | 0.83 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2GAAMMP2MMP9 | |
| SCHEMBL9765301 | 0.82 | ALDH1A1 (0.67) | ALDH1A1CYP1A2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL9765289 | 0.82 | NR3C1 (0.62) | SMN1; SMN2MEN1KMT2AL3MBTL1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0502498-A1 | Phenoxyalkanoic acid derivatives and process for preparation thereof | TANABE SEIYAKU CO., LTD. (JP) | 1992-09-09 | — | — | EP | disclosed |
| EP-0255728-B1 | PHENOXYACETIC ACID COMPOUNDS, THEIR PREPARATION, PHARMACEUTICAL COMPOSITION AND USE | TANABE SEIYAKU CO., LTD. (JP) | 1991-11-27 | — | — | EP | disclosed |
| CN-1011780-B | PROCESS FOR PRODUCING PHENOXYACETIC ACID DERIVATIVES | TANABE SEIYAKU CO (JP) | 1991-02-27 | — | — | CN | disclosed |
| US-4866196-A | ANTICOAGULANTS | TANABE SEIYAKU CO., LTD. (JP) | 1989-09-12 | — | — | US | disclosed |
| CN-87105501-A | New phenoxyacetic acid derivative and preparation method thereof and contain its and form as the medicine of activeconstituents | — | 1988-02-17 | — | — | CN | disclosed |
| EP-0255728-A2 | Phenoxyacetic acid compounds, their preparation, pharmaceutical composition and use | TANABE SEIYAKU CO., LTD. (JP) | 1988-02-10 | — | — | EP | disclosed |