Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | TRPC4 | Q9UBN4 | 1/20 | 0.40 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | BRAF | P15056 | 1/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9708117 | 0.93 | DCTPP1 (0.43) | DCTPP1SMN1; SMN2THRBUSP2KMT2A | |
| SCHEMBL9707598 | 0.92 | DCTPP1 (0.42) | DCTPP1KMT2AALDH1A1KDM4EMEN1 | |
| SCHEMBL9708292 | 0.92 | ADORA3 (0.42) | DCTPP1ADORA3 | |
| SCHEMBL9707506 | 0.92 | ADORA3 (0.42) | DCTPP1ADORA3 | |
| SCHEMBL9707578 | 0.91 | DCTPP1 (0.41) | DCTPP1KMT2AALDH1A1KDM4EMEN1 | |
| SCHEMBL9708690 | 0.91 | MAPT (0.42) | DPP4ALDH1A1KDM4EADORA3BRAF | |
| SCHEMBL9708557 | 0.90 | DCTPP1 (0.43) | DCTPP1THRBUSP2KMT2AALDH1A1 | |
| SCHEMBL9708355 | 0.90 | DCTPP1 (0.46) | DCTPP1SMN1; SMN2THRBKCNH2TRPC4 | |
| SCHEMBL9708258 | 0.90 | MAPT (0.43) | SMN1; SMN2DPP4KMT2AALDH1A1KDM4E | |
| SCHEMBL9708265 | 0.90 | DCTPP1 (0.41) | DCTPP1KMT2AALDH1A1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992007852-A1 | BIPHENYLALKYL XANTHINE COMPOUNDS FOR TREATMENT OF CARDIOVASCULAR DISORDERS | G.D. SEARLE & CO. (US) | 1992-05-14 | — | — | WO | disclosed |