Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | BRAF | P15056 | 1/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9707525 | 0.95 | ADORA2B (0.46) | ADORA3ADORA1ADORA2BADORA2A | |
| SCHEMBL9708258 | 0.94 | MAPT (0.43) | MAPTADORA3ADORA1ADORA2BADORA2A | |
| SCHEMBL9708256 | 0.93 | HPGD (0.44) | ADORA3ADORA2BADORA2A | |
| SCHEMBL9708614 | 0.91 | POLB (0.46) | MAPTADORA3ADORA2BKDM4EALDH1A1 | |
| SCHEMBL9708711 | 0.91 | ALOX15 (0.46) | MAPTALDH1A1DPP4BRAF | |
| SCHEMBL9707573 | 0.91 | DCTPP1 (0.51) | MAPTADORA3KDM4EALDH1A1DPP4 | |
| SCHEMBL9708337 | 0.90 | AGTR1 (0.44) | MAPTADORA3ADORA1ALDH1A1 | |
| SCHEMBL9708336 | 0.90 | ADORA3 (0.46) | ADORA3ADORA1ADORA2BADORA2A | |
| SCHEMBL9707901 | 0.90 | ADORA3 (0.40) | ADORA3ADORA1ADORA2BADORA2A | |
| SCHEMBL9707551 | 0.90 | ADORA3 (0.46) | ADORA3ADORA1ADORA2BADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992007852-A1 | BIPHENYLALKYL XANTHINE COMPOUNDS FOR TREATMENT OF CARDIOVASCULAR DISORDERS | G.D. SEARLE & CO. (US) | 1992-05-14 | — | — | WO | disclosed |