Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | BRAF | P15056 | 1/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.39 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.39 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9708690 | 0.94 | MAPT (0.42) | MAPTDPP4BRAFPIK3CGALDH1A1 | |
| SCHEMBL9709012 | 0.93 | PDE5A (0.42) | ADORA3ADORA2AADORA1AGTR1AGTR2 | |
| SCHEMBL9708711 | 0.92 | ALOX15 (0.46) | MAPTDPP4BRAFLMNAALDH1A1 | |
| SCHEMBL9708813 | 0.91 | RAB9A (0.44) | MAPTDPP4BRAFPIK3CGLMNA | |
| SCHEMBL9708614 | 0.91 | POLB (0.46) | MAPTBRAFPIK3CGLMNAALDH1A1 | |
| SCHEMBL9708840 | 0.90 | AGTR1 (0.44) | MAPTDPP4BRAFPIK3CGALDH1A1 | |
| SCHEMBL9707701 | 0.90 | ADORA1 (0.44) | ADORA3ADORA2AADORA2BADORA1AGTR1 | |
| SCHEMBL9707573 | 0.90 | DCTPP1 (0.51) | MAPTDPP4BRAFPIK3CGALDH1A1 | |
| SCHEMBL9707578 | 0.89 | DCTPP1 (0.41) | ALDH1A1KDM4EADORA3ADORA2AADORA2B | |
| SCHEMBL9708372 | 0.89 | AGTR1 (0.39) | ADORA3ADORA2AADORA1KMT2AAGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992007852-A1 | BIPHENYLALKYL XANTHINE COMPOUNDS FOR TREATMENT OF CARDIOVASCULAR DISORDERS | G.D. SEARLE & CO. (US) | 1992-05-14 | — | — | WO | disclosed |