Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TPH2 | Q8IWU9 | 13/20 | 0.43 |
| ▸ | TPH1 | P17752 | 12/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.40 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.40 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9707464 | 0.93 | MEN1 (0.45) | MEN1KMT2AKDM4ETSHRNPSR1 | |
| SCHEMBL9707557 | 0.92 | ALDH1A1 (0.43) | MEN1KMT2AKDM4ETSHRNPSR1 | |
| SCHEMBL9708303 | 0.91 | ALDH1A1 (0.44) | MEN1KMT2AKDM4ETSHRNPSR1 | |
| SCHEMBL9708130 | 0.90 | CXCL8 (0.49) | MEN1KMT2AKDM4ETSHRNPSR1 | |
| SCHEMBL9707717 | 0.89 | ALDH1A1 (0.49) | MEN1KMT2AKDM4ENPSR1HSD17B10 | |
| SCHEMBL9708857 | 0.89 | ALDH1A1 (0.39) | MEN1KMT2AKDM4ETSHRNPSR1 | |
| SCHEMBL9708300 | 0.89 | MEN1 (0.42) | MEN1KMT2AKDM4ETSHRNPSR1 | |
| SCHEMBL9707767 | 0.89 | MEN1 (0.50) | MEN1KMT2AKDM4ETSHRNPSR1 | |
| SCHEMBL9708009 | 0.88 | CXCL8 (0.39) | MEN1KMT2AKDM4ETSHRNPSR1 | |
| SCHEMBL9708297 | 0.88 | MEN1 (0.54) | MEN1KMT2ATPH2TPH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992007852-A1 | BIPHENYLALKYL XANTHINE COMPOUNDS FOR TREATMENT OF CARDIOVASCULAR DISORDERS | G.D. SEARLE & CO. (US) | 1992-05-14 | — | — | WO | disclosed |