Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 2/20 | 0.35 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.35 |
| ▸ | USP1 | O94782 | 2/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9708894 | 0.95 | AGTR1 (0.35) | AGTR1AGTR2USP1 | |
| SCHEMBL9707862 | 0.92 | PPARG (0.37) | USP1 | |
| SCHEMBL9708639 | 0.92 | AGTR1 (0.35) | AGTR1AGTR2PDE4AKMT2APDE4B | |
| SCHEMBL9707891 | 0.91 | AGTR1 (0.35) | AGTR1AGTR2USP1PDE4AKMT2A | |
| SCHEMBL9708160 | 0.90 | AGTR1 (0.37) | AGTR1AGTR2USP1 | |
| SCHEMBL9707924 | 0.90 | AGTR1 (0.40) | AGTR1AGTR2 | |
| SCHEMBL9707857 | 0.90 | ALDH1A1 (0.38) | USP1 | |
| SCHEMBL9708049 | 0.89 | USP1 (0.34) | USP1 | |
| SCHEMBL9707685 | 0.89 | PPARG (0.35) | AGTR1AGTR2 | |
| SCHEMBL9707660 | 0.89 | USP1 (0.39) | AGTR1AGTR2USP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992007852-A1 | BIPHENYLALKYL XANTHINE COMPOUNDS FOR TREATMENT OF CARDIOVASCULAR DISORDERS | G.D. SEARLE & CO. (US) | 1992-05-14 | — | — | WO | disclosed |