Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 1/20 | 0.35 |
| ▸ | KCNA4 | P22459 | 1/20 | 0.34 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.34 |
| ▸ | KCNAB1 | Q14722 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.32 |
| ▸ | STAT6 | P42226 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | GMNN | O75496 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9708741 | 0.90 | FFAR3 (0.38) | FFAR3KCNA4KCNA1KCNAB1MAPK1 | |
| SCHEMBL42141 | 0.77 | FFAR3 (0.52) | FFAR3KCNA4KCNA1KCNAB1MAPK1 | |
| Hydrochloric Acid SCHEMBL15522635 | 0.75 | FFAR3 (0.50) | FFAR3KCNA4KCNA1KCNAB1MAPK1 | |
| SCHEMBL18105045 | 0.74 | ATM (0.38) | MAPK1LMNASMN1; SMN2 | |
| SCHEMBL1970312 | 0.74 | KCNA4 (0.39) | FFAR3KCNA4KCNA1KCNAB1 | |
| SCHEMBL16837867 | 0.71 | DGAT1 (0.31) | SMN1; SMN2 | |
| SCHEMBL15448047 | 0.71 | ATM (0.39) | MAPK1LMNASMN1; SMN2 | |
| SCHEMBL769660 | 0.71 | — | — | |
| SCHEMBL5590449 | 0.70 | KCNA4 (0.33) | KCNA4KCNA1KCNAB1 | |
| SCHEMBL12731596 | 0.70 | FFAR3 (0.33) | FFAR3KCNA4KCNA1KCNAB1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104781261-A | Macrocyclic inhibitors of flaviviridae viruses | GILEAD SCIENCES INC | 2015-07-15 | — | — | CN | disclosed |