Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNOT7 | Q9UIV1 | 2/20 | 0.53 |
| ▸ | PARN | O95453 | 1/20 | 0.53 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.48 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.46 |
| ▸ | BRD4 | O60885 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | DAO | P14920 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.42 |
| ▸ | PNP | P00491 | 1/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL554897 | 0.92 | CNOT7 (0.61) | CNOT7PARNSMN1; SMN2ALDH1A1GDA | |
| SCHEMBL16028459 | 0.85 | BRD4 (0.50) | CNOT7PARNCYP11B1CYP11B2SMN1; SMN2 | |
| SCHEMBL27394380 | 0.81 | GDA (0.48) | CNOT7PARNCYP11B1CYP11B2ALDH1A1 | |
| SCHEMBL9708858 | 0.80 | CNOT7 (0.40) | CNOT7PARNSMN1; SMN2ALDH1A1GDA | |
| SCHEMBL27582867 | 0.78 | CNOT7 (0.63) | CNOT7PARNALDH1A1GDADAO | |
| SCHEMBL21883489 | 0.77 | SMN1; SMN2 (0.56) | CNOT7PARNCYP11B1CYP11B2SMN1; SMN2 | |
| SCHEMBL7973938 | 0.77 | CNOT7 (0.48) | CNOT7PARNCYP11B1CYP11B2SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7017127 | 0.77 | VNN1 (0.44) | CNOT7PARNSMN1; SMN2ALDH1A1GDA | |
| SCHEMBL22800917 | 0.76 | LMNA (0.46) | CNOT7PARNALDH1A1GDAKMT2A | |
| SCHEMBL7977499 | 0.76 | CYP11B1 (0.48) | CNOT7PARNCYP11B1CYP11B2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992007852-A1 | BIPHENYLALKYL XANTHINE COMPOUNDS FOR TREATMENT OF CARDIOVASCULAR DISORDERS | G.D. SEARLE & CO. (US) | 1992-05-14 | — | — | WO | disclosed |