Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 8/20 | 0.38 |
| ▸ | AGTR2 | P50052 | 8/20 | 0.38 |
| ▸ | USP1 | O94782 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9707720 | 0.88 | AGTR1 (0.43) | DPP4AGTR1AGTR2 | |
| SCHEMBL9707628 | 0.86 | AGTR1 (0.50) | DPP4AGTR1AGTR2 | |
| SCHEMBL9707407 | 0.86 | GPR18 (0.39) | AGTR1AGTR2USP1 | |
| SCHEMBL9708314 | 0.85 | ADORA2B (0.38) | AGTR1AGTR2USP1 | |
| SCHEMBL9708752 | 0.85 | AGTR1 (0.51) | AGTR1AGTR2 | |
| SCHEMBL9707736 | 0.84 | ADORA3 (0.42) | USP1 | |
| SCHEMBL9708130 | 0.84 | CXCL8 (0.49) | DPP4 | |
| SCHEMBL9708173 | 0.84 | AGTR1 (0.41) | DPP4AGTR1AGTR2 | |
| SCHEMBL9708424 | 0.84 | ADORA2B (0.40) | AGTR1AGTR2USP1 | |
| SCHEMBL9707370 | 0.84 | PPARG (0.36) | AGTR1AGTR2USP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992007852-A1 | BIPHENYLALKYL XANTHINE COMPOUNDS FOR TREATMENT OF CARDIOVASCULAR DISORDERS | G.D. SEARLE & CO. (US) | 1992-05-14 | — | — | WO | disclosed |