Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.41 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.40 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.40 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | ABCC9 | O60706 | 2/20 | 0.40 |
| ▸ | ABCC8 | Q09428 | 2/20 | 0.40 |
| ▸ | KCNJ11 | Q14654 | 2/20 | 0.40 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9708747 | 0.80 | ALDH1A1 (0.48) | HPGDRAB9ANPC1ALDH1A1L3MBTL1 | |
| SCHEMBL11713193 | 0.78 | ALDH1A1 (0.66) | HPGDRAB9ANPC1ALDH1A1L3MBTL1 | |
| SCHEMBL1876681 | 0.73 | TSHR (0.42) | ALDH1A1KMT2A | |
| SCHEMBL11711734 | 0.71 | L3MBTL1 (0.63) | RAB9AALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL3147633 | 0.70 | ALDH1A1 (0.58) | HPGDRAB9ANPC1ALDH1A1L3MBTL1 | |
| Benzophenone SCHEMBL27422465 | 0.69 | ALDH1A1 (0.78) | HPGDRAB9ANPC1ALDH1A1L3MBTL1 | |
| SCHEMBL11233382 | 0.68 | HPGD (0.64) | HPGDRAB9ANPC1ALDH1A1L3MBTL1 | |
| SCHEMBL9709124 | 0.67 | ALDH1A1 (0.54) | HPGDRAB9ANPC1ALDH1A1L3MBTL1 | |
| SCHEMBL8074109 | 0.67 | ALDH1A1 (0.52) | RAB9ANPC1ALDH1A1L3MBTL1MEN1 | |
| SCHEMBL9066312 | 0.66 | ALDH1A1 (0.93) | HPGDRAB9ANPC1ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0487423-A1 | Benzoselenazolinone derivatives, their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1992-05-27 | — | — | EP | claimed |