Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.45 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.45 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7268018 | 0.88 | KDM4E (0.65) | POLBSMN1; SMN2KDM4EGAAMAPT | |
| SCHEMBL9708987 | 0.86 | POLB (0.51) | POLBSMN1; SMN2KDM4EGAAMAPT | |
| SCHEMBL15720901 | 0.82 | KDM4E (0.73) | POLBSMN1; SMN2KDM4EGAAMAPT | |
| SCHEMBL7273776 | 0.78 | L3MBTL1 (0.59) | POLBSMN1; SMN2KDM4EGAAMAPT | |
| SCHEMBL9709038 | 0.75 | TSHR (0.59) | POLBSMN1; SMN2KDM4EGAAMAPT | |
| SCHEMBL9750783 | 0.74 | ALDH1A1 (0.51) | POLBSMN1; SMN2KDM4EGAAMAPT | |
| SCHEMBL7055109 | 0.74 | CARM1 (0.75) | SMN1; SMN2KDM4ETSHRALDH1A1CYP3A4 | |
| SCHEMBL11639395 | 0.73 | ALDH1A1 (0.61) | SMN1; SMN2ALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL4740336 | 0.71 | KDM4E (0.68) | SMN1; SMN2KDM4EGAAMAPTALDH1A1 | |
| SCHEMBL11113048 | 0.71 | KDM4E (0.51) | POLBSMN1; SMN2KDM4EGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0293925-A2 | Compound active in cardiovascular therapy | SIMES, SOCIETA ITALIANA MEDICINALI E SINTETICI, S.P.A. (IT) | 1988-12-07 | — | — | EP | disclosed |