SCHEMBL9709284

SCHEMBL9709284

CC(C)C(C(=O)O)=C(C(=O)O)c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 1/20 0.44
PGR P06401 1/20 0.43
ADRA2A P08913 1/20 0.43
ADRA2B P18089 1/20 0.43
HTR2A P28223 1/20 0.43
HRH1 P35367 1/20 0.43
KCNH2 Q12809 1/20 0.43
SMN1; SMN2 Q16637 2/20 0.42
NPSR1 Q6W5P4 2/20 0.42
MAPT P10636 2/20 0.42
LMNA P02545 1/20 0.42
XBP1 P17861 1/20 0.42
ATM Q13315 1/20 0.42
CES2 O00748 4/20 0.41
CES1 P23141 4/20 0.41
TSHR P16473 3/20 0.41
ALDH1A1 P00352 2/20 0.41
DAO P14920 1/20 0.41
NAPRT Q6XQN6 1/20 0.41
HPGD P15428 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9709278 1.00 CYP2C9 (0.44) CYP2C9PGRADRA2AADRA2BHTR2A
SCHEMBL3514047 0.79 ALDH1A1 (0.50) PGRADRA2AADRA2BHTR2AHRH1
SCHEMBL1173261 0.79 PGR (0.43) PGRADRA2AADRA2BHTR2AHRH1
SCHEMBL23721593 0.78 HPGD (0.44) CYP2C9SMN1; SMN2MAPTLMNAALDH1A1
SCHEMBL26080871 0.78 PGR (0.42) PGRADRA2AADRA2BHTR2AHRH1
SCHEMBL114583 0.77 CES1 (0.58) SMN1; SMN2MAPTLMNAATMCES2
SCHEMBL183462 0.77 CES1 (0.58) SMN1; SMN2MAPTLMNAATMCES2
SCHEMBL523842 0.77 CES1 (0.58) SMN1; SMN2MAPTLMNAATMCES2
SCHEMBL13505417 0.75 PGR (0.47) PGRADRA2AADRA2BHTR2AHRH1
Toluene SCHEMBL1083282 0.74 LMNA (0.50) PGRADRA2AADRA2BHTR2AHRH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0244835-B1 LANGMUIR-BLODGETT ULTRATHIN MEMBRANE OF POLYFUMURATE NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1992-08-26 EP claimed
EP-0233299-B1 OPTICAL RESIN AND PROCESS FOR PREPARING THE SAME NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1991-03-13 EP claimed