SCHEMBL1173261

SCHEMBL1173261

CC(C)C(C(=O)O)=C(c1ccccc1)C(C)C

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PGR P06401 1/20 0.43
ADRA2A P08913 1/20 0.43
ADRA2B P18089 1/20 0.43
HTR2A P28223 1/20 0.43
HRH1 P35367 1/20 0.43
KCNH2 Q12809 1/20 0.43
SMN1; SMN2 Q16637 3/20 0.42
MAPT P10636 3/20 0.42
NPSR1 Q6W5P4 2/20 0.42
LMNA P02545 1/20 0.42
XBP1 P17861 1/20 0.42
ATM Q13315 1/20 0.42
CES1 P23141 5/20 0.41
TDP1 Q9NUW8 3/20 0.41
HPGD P15428 2/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
CYP3A4 P08684 2/20 0.41
KDM4E B2RXH2 1/20 0.41
ALOX15 P16050 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6472265 0.83 CES1 (0.45) PGRADRA2AADRA2BHTR2AHRH1
SCHEMBL17428 0.81 TSHR (0.47) PGRADRA2AADRA2BHTR2AHRH1
SCHEMBL31119064 0.81 TSHR (0.47) PGRADRA2AADRA2BHTR2AHRH1
SCHEMBL15673297 0.81 SMN1; SMN2 (0.44) PGRADRA2AADRA2BHTR2AHRH1
SCHEMBL9709284 0.79 CYP2C9 (0.44) PGRADRA2AADRA2BHTR2AHRH1
SCHEMBL9709278 0.79 CYP2C9 (0.44) PGRADRA2AADRA2BHTR2AHRH1
SCHEMBL26080871 0.78 PGR (0.42) PGRADRA2AADRA2BHTR2AHRH1
SCHEMBL2480694 0.77 ERCC5 (0.46) SMN1; SMN2HPGDKMT2ACYP3A4KDM4E
SCHEMBL15513 0.77 ALDH1A1 (0.51) PGRADRA2AADRA2BHTR2AHRH1
SCHEMBL5271348 0.76 CLCN2 (0.41) PGRADRA2AADRA2BHTR2AHRH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 243 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2874507-B1 AQUEOUS TRANSPARENT OIL-IN-WATER EMULSION COMPRISING AN EMULSIFIED CAROTENOID BASF SE (DE) 2020-12-30 EP claimed
CN-105997532-B Oil-in-water type emulsion cosmetic 花王株式会社 2020-09-22 CN claimed
EP-3307395-B1 SOLUBILISING AGENTS FOR UV SCREENING COMPOUNDS ISP INVESTMENTS LLC (US) 2020-08-05 EP claimed
EP-2485807-B1 SUN-CARE COMPOSITIONS ISP INVESTMENTS LLC (US) 2019-07-03 EP claimed
EP-2687103-B1 Process for manufacturing an aqueous transparent oil-in-water emulsion comprising a carotenoid and emulsion produced BASF SE (DE) 2019-05-22 EP claimed
CN-105997532-A Oil-in-water-type emulsion cosmetic 花王株式会社 2016-10-12 CN claimed
CN-103974687-A Oil-in-water type emulsion cosmetic KAO CORP 2014-08-06 CN claimed
EP-1595936-B1 COMPOSITION FOR EXTERNAL USE VITAMIN C60 BIORES CORP (JP) 2011-10-19 EP claimed
EP-1107728-B1 COSMETIC COMPOSITIONS FOR SOLAR PROTECTION AND USES OREAL (FR) 2004-04-28 EP claimed
EP-1002523-B1 Cosmetic sunscreening compositions OREAL (FR) 2004-03-03 EP claimed
EP-1107728-A1 COSMETIC COMPOSITIONS FOR SOLAR PROTECTION AND USES L'Oreal (FR) 2001-06-20 EP claimed
WO-2001001946-A1 COSMETIC COMPOSITIONS FOR SOLAR PROTECTION AND USES L'OREAL (FR) 2001-01-11 WO claimed
EP-1002523-A1 Cosmetic sunscreening compositions L'OREAL (FR) 2000-05-24 EP claimed
US-12605315-B2 External skin preparation KAO CORPORATION (JP) 2026-04-21 US disclosed
US-12551424-B2 Oil-in-water type emulsification composition containing UV wavelength conversion substance SHISEIDO COMPANY, LTD. (JP) 2026-02-17 US disclosed
US-12440431-B2 Cosmetic comprising ultraviolet wavelength conversion substance SHISEIDO COMPANY, LTD. (JP) 2025-10-14 US disclosed
US-5776438-A MIXTURE OF TOCOPHEROL-2-ASCORBIC ACIDPHOSPHORIC ACID DIESTERSAND AN ULTRAVIOLET RADIATION ABSORBER SHISEIDO CO., LTD. (JP) 1998-07-07 US disclosed
EP-0506961-B1 EXTERNAL PREPARATION FOR SKIN SHISEIDO CO LTD (JP) 1995-12-20 EP disclosed
US-5415875-A Applying hydrolyzed shell membrane and tocopherol derivative; aging and oxidation resistance SHISEIDO CO., LTD. (JP) 1995-05-16 US disclosed
EP-0506961-A1 EXTERNAL PREPARATION FOR SKIN SHISEIDO COMPANY LIMITED (JP) 1992-10-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12605315-B2 External skin preparation TLR5, CUTA, TLR3 PGR 608/4885ADRA2A 2712/4885ADRA2B 2535/4885
US-12551424-B2 Oil-in-water type emulsification composition containing UV wavelength conversion substance PCNA, CD14, TP53 PGR 73/4885ADRA2A 4844/4885ADRA2B 4724/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.