Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23519079 | 0.76 | NOTUM (0.41) | NOTUM | |
| SCHEMBL10968659 | 0.71 | — | — | |
| SCHEMBL19865289 | 0.71 | NOTUM (0.36) | NOTUMMAPT | |
| SCHEMBL15419843 | 0.71 | CES2 (0.41) | NOTUMCA1CA2MAPT | |
| SCHEMBL23447294 | 0.69 | NOTUM (0.43) | NOTUM | |
| SCHEMBL24361437 | 0.69 | NOTUM (0.46) | TSHRSMN1; SMN2NOTUMHSD17B10L3MBTL1 | |
| SCHEMBL5169953 | 0.69 | NOTUM (0.46) | NOTUMMAPT | |
| SCHEMBL23519080 | 0.69 | PTGS2 (0.39) | TSHRSMN1; SMN2NOTUMHSD17B10CA1 | |
| SCHEMBL23519003 | 0.69 | NOTUM (0.36) | NOTUMPOLB | |
| SCHEMBL31181867 | 0.68 | TSHR (0.36) | TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5142063-A | For hydrogenation of alpha-beta unsaturated acids and esters alpha-meto lactones and alpha-keto acids or esters | HOFFMANN-LA ROCHE, INC. (US) | 1992-08-25 | — | — | US | disclosed |