Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27396003 | 0.79 | ALDH1A1 (0.34) | ALDH1A1LMNATSHR | |
| SCHEMBL13328802 | 0.77 | ALDH1A1 (0.33) | ALDH1A1LMNA | |
| SCHEMBL28349338 | 0.77 | ABCC4 (0.35) | ALDH1A1LMNATSHR | |
| SCHEMBL9709901 | 0.77 | SLC1A2 (0.38) | ALDH1A1 | |
| SCHEMBL9732893 | 0.77 | MAPT (0.39) | ALDH1A1LMNATSHR | |
| SCHEMBL2028241 | 0.75 | ALDH1A1 (0.32) | ALDH1A1LMNA | |
| SCHEMBL1568673 | 0.75 | ALDH1A1 (0.32) | ALDH1A1LMNA | |
| SCHEMBL5831688 | 0.75 | ALDH1A1 (0.58) | ALDH1A1LMNATSHR | |
| SCHEMBL2027868 | 0.75 | ALDH1A1 (0.32) | ALDH1A1LMNA | |
| SCHEMBL9732270 | 0.73 | LMNA (0.35) | ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5153214-A | Treating cardiovascular disorders | CIBA-GEIGY CORPORATION (US) | 1992-10-06 | — | — | US | disclosed |
| EP-0493324-A1 | Certain (arylsulfonamido- and pyridyl- or imidazolyl-)-substituted carboxylic acids and derivatives thereof | CIBA-GEIGY AG (CH) | 1992-07-01 | — | — | EP | disclosed |
| US-5025025-A | Cardiovascular disorders | CIBA-GEIGY CORPORATION (US) | 1991-06-18 | — | — | US | disclosed |
| EP-0405391-A1 | Certain (arylsulfonamido- and pyridyl- or imidazolyl-)-substituted carboxylic acids and derivatives thereof | CIBA-GEIGY AG (CH) | 1991-01-02 | — | — | EP | disclosed |