Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8636592 | 0.79 | ACHE (0.37) | — | |
| SCHEMBL9360177 | 0.79 | ACHE (0.37) | — | |
| SCHEMBL2347801 | 0.79 | — | — | |
| SCHEMBL5489483 | 0.77 | CA2 (0.35) | DAOCA2 | |
| SCHEMBL2348604 | 0.77 | CA2 (0.35) | DAOCA2 | |
| SCHEMBL6151243 | 0.77 | CA2 (0.35) | DAOCA2 | |
| SCHEMBL28586110 | 0.75 | — | — | |
| SCHEMBL10359721 | 0.73 | KEAP1 (0.36) | — | |
| SCHEMBL9295327 | 0.73 | CA2 (0.33) | DAOCA2 | |
| SCHEMBL2347948 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5153214-A | Treating cardiovascular disorders | CIBA-GEIGY CORPORATION (US) | 1992-10-06 | — | — | US | disclosed |
| EP-0493324-A1 | Certain (arylsulfonamido- and pyridyl- or imidazolyl-)-substituted carboxylic acids and derivatives thereof | CIBA-GEIGY AG (CH) | 1992-07-01 | — | — | EP | disclosed |
| US-5025025-A | Cardiovascular disorders | CIBA-GEIGY CORPORATION (US) | 1991-06-18 | — | — | US | disclosed |
| EP-0405391-A1 | Certain (arylsulfonamido- and pyridyl- or imidazolyl-)-substituted carboxylic acids and derivatives thereof | CIBA-GEIGY AG (CH) | 1991-01-02 | — | — | EP | disclosed |