Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TEAD3 | Q99594 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.35 |
| ▸ | NAAA | Q02083 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | GBA1 | P04062 | 2/20 | 0.35 |
| ▸ | UGCG | Q16739 | 2/20 | 0.35 |
| ▸ | GBA2 | Q9HCG7 | 2/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29344721 | 0.87 | TSHR (0.47) | TEAD3TSHRKDM4EPOLBTDP1 | |
| SCHEMBL9709696 | 0.84 | TEAD3 (0.44) | TEAD3KDM4ETDP1L3MBTL1NAAA | |
| SCHEMBL16370105 | 0.84 | SLC1A3 (0.39) | TSHRTDP1L3MBTL1SMN1; SMN2 | |
| SCHEMBL9709157 | 0.80 | TEAD3 (0.40) | TEAD3KDM4ENAAAHTTSMN1; SMN2 | |
| SCHEMBL9709745 | 0.79 | TDP1 (0.41) | TEAD3TSHRPOLBTDP1L3MBTL1 | |
| SCHEMBL1964292 | 0.78 | ALDH1A1 (0.40) | TSHRKDM4EPOLBCA1CA2 | |
| SCHEMBL9709543 | 0.78 | TBXAS1 (0.41) | TEAD3NAAA | |
| SCHEMBL9709669 | 0.78 | TEAD3 (0.41) | TEAD3TSHRKDM4ETDP1L3MBTL1 | |
| SCHEMBL9709674 | 0.78 | TEAD3 (0.41) | TEAD3TSHRKDM4ETDP1L3MBTL1 | |
| SCHEMBL9709483 | 0.77 | TEAD3 (0.44) | TEAD3TSHRKDM4ETDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0493324-A1 | Certain (arylsulfonamido- and pyridyl- or imidazolyl-)-substituted carboxylic acids and derivatives thereof | CIBA-GEIGY AG (CH) | 1992-07-01 | — | — | EP | disclosed |