Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | TEAD3 | Q99594 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | CTSB | P07858 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.33 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | NAAA | Q02083 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9709525 | 0.81 | TDP1 (0.41) | TDP1TEAD3MAPTMEN1KMT2A | |
| SCHEMBL9709529 | 0.81 | TDP1 (0.41) | TDP1TEAD3MAPTMEN1KMT2A | |
| SCHEMBL9709636 | 0.79 | TEAD3 (0.41) | TDP1TEAD3L3MBTL1POLBCA1 | |
| SCHEMBL9709696 | 0.77 | TEAD3 (0.44) | TDP1TEAD3MAPTMEN1KMT2A | |
| SCHEMBL17202064 | 0.77 | PLA2G2A (0.52) | PLA2G10PLA2G2A | |
| SCHEMBL2076982 | 0.77 | ALDH1A1 (0.47) | TDP1TEAD3L3MBTL1ALDH1A1CA1 | |
| SCHEMBL20294565 | 0.75 | ALDH1A1 (0.45) | TDP1L3MBTL1ALDH1A1CA1CA2 | |
| SCHEMBL9709157 | 0.75 | TEAD3 (0.40) | TEAD3MAPTALDH1A1NAAAHTT | |
| SCHEMBL19868233 | 0.75 | CA1 (0.42) | TDP1MAPTPLA2G10PLA2G2ACA1 | |
| SCHEMBL27032342 | 0.74 | L3MBTL1 (0.37) | TDP1L3MBTL1CTSBALDH1A1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0493324-A1 | Certain (arylsulfonamido- and pyridyl- or imidazolyl-)-substituted carboxylic acids and derivatives thereof | CIBA-GEIGY AG (CH) | 1992-07-01 | — | — | EP | disclosed |