Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | PTAFR | P25105 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9709491 | 0.82 | KDM4E (0.40) | ALDH1A1LMNA | |
| SCHEMBL9709157 | 0.76 | TEAD3 (0.40) | FAAHALDH1A1LMNA | |
| SCHEMBL9709586 | 0.75 | TBXAS1 (0.62) | TBXAS1 | |
| SCHEMBL9709801 | 0.75 | TBXAS1 (0.52) | TBXAS1 | |
| SCHEMBL9709805 | 0.75 | TBXAS1 (0.52) | TBXAS1 | |
| SCHEMBL9709655 | 0.73 | TBXAS1 (0.58) | TBXAS1FAAH | |
| SCHEMBL9709646 | 0.73 | TBXAS1 (0.58) | TBXAS1FAAH | |
| SCHEMBL11512794 | 0.73 | TBXAS1 (0.39) | LTA4HTBXAS1 | |
| SCHEMBL9709445 | 0.73 | TBXAS1 (0.41) | KMT2ATBXAS1CHRNB2CHRNA4ALDH1A1 | |
| SCHEMBL9709449 | 0.73 | TBXAS1 (0.41) | KMT2ATBXAS1CHRNB2CHRNA4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0493324-A1 | Certain (arylsulfonamido- and pyridyl- or imidazolyl-)-substituted carboxylic acids and derivatives thereof | CIBA-GEIGY AG (CH) | 1992-07-01 | — | — | EP | disclosed |