Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 9/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | HRH2 | P25021 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9709445 | 1.00 | TBXAS1 (0.41) | TBXAS1NAMPTCHRNB2CHRNA4HRH2 | |
| SCHEMBL9709543 | 0.81 | TBXAS1 (0.41) | TBXAS1ALDH1A1TBXA2RKMT2A | |
| SCHEMBL9709667 | 0.73 | LTA4H (0.43) | TBXAS1CHRNB2CHRNA4ALDH1A1LMNA | |
| SCHEMBL9709484 | 0.72 | TBXAS1 (0.47) | TBXAS1CHRNB2CHRNA4HRH2HRH1 | |
| SCHEMBL9709487 | 0.72 | TBXAS1 (0.47) | TBXAS1CHRNB2CHRNA4HRH2HRH1 | |
| SCHEMBL9709157 | 0.71 | TEAD3 (0.40) | ALDH1A1LMNA | |
| SCHEMBL9709504 | 0.71 | TBXAS1 (0.43) | TBXAS1ALDH1A1TDP1 | |
| SCHEMBL2722347 | 0.70 | ALOX5 (0.53) | ALDH1A1TDP1 | |
| SCHEMBL14423635 | 0.70 | TBXAS1 (0.70) | TBXAS1CHRNB2CHRNA4ALDH1A1LMNA | |
| SCHEMBL9212182 | 0.69 | ALOX5 (0.52) | TBXAS1ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0493324-A1 | Certain (arylsulfonamido- and pyridyl- or imidazolyl-)-substituted carboxylic acids and derivatives thereof | CIBA-GEIGY AG (CH) | 1992-07-01 | — | — | EP | disclosed |