Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 19/20 | 0.52 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.48 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9709805 | 1.00 | TBXAS1 (0.52) | TBXAS1TBXA2RCHRNA7 | |
| SCHEMBL9709520 | 0.78 | MMP3 (0.42) | — | |
| SCHEMBL9709518 | 0.78 | MMP3 (0.42) | — | |
| SCHEMBL9709646 | 0.76 | TBXAS1 (0.58) | TBXAS1TBXA2R | |
| SCHEMBL9709655 | 0.76 | TBXAS1 (0.58) | TBXAS1TBXA2R | |
| SCHEMBL6642234 | 0.76 | TBXAS1 (0.60) | TBXAS1CHRNA7 | |
| SCHEMBL4769249 | 0.76 | HRH4 (0.57) | TBXAS1CHRNA7 | |
| SCHEMBL9732228 | 0.75 | TBXAS1 (0.49) | TBXAS1TBXA2R | |
| SCHEMBL10972402 | 0.75 | TBXAS1 (0.68) | TBXAS1CHRNA7 | |
| SCHEMBL9709667 | 0.75 | LTA4H (0.43) | TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5153214-A | Treating cardiovascular disorders | CIBA-GEIGY CORPORATION (US) | 1992-10-06 | — | — | US | disclosed |
| EP-0493324-A1 | Certain (arylsulfonamido- and pyridyl- or imidazolyl-)-substituted carboxylic acids and derivatives thereof | CIBA-GEIGY AG (CH) | 1992-07-01 | — | — | EP | disclosed |