Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 6/20 | 0.43 |
| ▸ | AGTR2 | P50052 | 6/20 | 0.43 |
| ▸ | ACP1 | P24666 | 8/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9709787 | 0.86 | LMNA (0.52) | ACP1LMNA | |
| SCHEMBL9709757 | 0.86 | AGTR1 (0.52) | AGTR1AGTR2ACP1 | |
| SCHEMBL9709673 | 0.79 | PDE4A (0.47) | AGTR1AGTR2ACP1 | |
| SCHEMBL2142522 | 0.78 | AGTR1 (0.70) | AGTR1AGTR2 | |
| SCHEMBL29681307 | 0.78 | AGTR1 (0.70) | AGTR1AGTR2 | |
| Hydrochloric Acid SCHEMBL9206106 | 0.78 | AGTR1 (0.36) | AGTR1AGTR2 | |
| SCHEMBL9709710 | 0.78 | PDE4A (0.51) | AGTR1AGTR2ACP1 | |
| Hydrochloric Acid SCHEMBL4126842 | 0.77 | AGTR1 (0.69) | AGTR1AGTR2 | |
| SCHEMBL9709791 | 0.77 | LMNA (0.48) | KDRLMNA | |
| SCHEMBL7447901 | 0.77 | AGTR1 (0.41) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992022533-A1 | 4-AMINOQUINOLINES AND PHARMACEUTICAL COMPOSITIONS THEREOF | THE UPJOHN COMPANY (US) | 1992-12-23 | — | — | WO | claimed |
| WO-1992022533-A1 | 4-AMINOQUINOLINES AND PHARMACEUTICAL COMPOSITIONS THEREOF | THE UPJOHN COMPANY (US) | 1992-12-23 | — | — | WO | disclosed |