SCHEMBL9709937

SCHEMBL9709937

C(=NON=Cc1ccccc1)c1ccccc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.57
L3MBTL1 Q9Y468 1/20 0.57
PLA2G7 Q13093 2/20 0.52
NOX1 Q9Y5S8 1/20 0.44
GRIN2D O15399 2/20 0.43
GRIN3B O60391 2/20 0.43
GRIN1 Q05586 2/20 0.43
GRIN2A Q12879 2/20 0.43
GRIN2B Q13224 2/20 0.43
GRIN2C Q14957 2/20 0.43
GRIN3A Q8TCU5 2/20 0.43
TAAR1 Q96RJ0 2/20 0.43
GAA P10253 2/20 0.43
NPC1 O15118 2/20 0.43
RAB9A P51151 2/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
MIF P14174 1/20 0.41
MAPT P10636 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27702975 0.79 LMNA (0.52) LMNAL3MBTL1PLA2G7NOX1GRIN2D
SCHEMBL11211453 0.79 LMNA (0.52) LMNAL3MBTL1PLA2G7NOX1GRIN2D
SCHEMBL10797604 0.79 LMNA (0.52) LMNAL3MBTL1PLA2G7NOX1GRIN2D
SCHEMBL1797264 0.79 LMNA (0.52) LMNAL3MBTL1PLA2G7NOX1GRIN2D
SCHEMBL113602 0.79 LMNA (0.52) LMNAL3MBTL1PLA2G7NOX1GRIN2D
SCHEMBL11211452 0.79 LMNA (0.52) LMNAL3MBTL1PLA2G7NOX1GRIN2D
SCHEMBL113601 0.79 LMNA (0.52) LMNAL3MBTL1PLA2G7NOX1GRIN2D
SCHEMBL1797266 0.79 LMNA (0.52) LMNAL3MBTL1PLA2G7NOX1GRIN2D
SCHEMBL28901973 0.79 LMNA (0.52) LMNAL3MBTL1PLA2G7NOX1GRIN2D
SCHEMBL25645476 0.79 LMNA (0.52) LMNAL3MBTL1PLA2G7NOX1GRIN2D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103922904-B A kind of method of synthetic 2-fluorinated aryl carbonyls JIANG University OF TECHNOLOGY (CN) 2016-05-18 CN disclosed
CN-103922904-A Method for synthesizing 2-fluoroarylcarbonyl compounds UNIV ZHEJIANG TECHNOLOGY 2014-07-16 CN disclosed
CN-101648887-B Method for synthesizing o-trans-(3-Cl-2-propenyl) hydroxylamine hydrochloride NINGBO OCEAN CHEMICAL NEW MATERIAL TECHNOLOGY CO LTD 2012-08-15 CN disclosed
CN-101648887-A Method for synthesizing o-trans-(3-Cl-2-propenyl) hydroxylamine hydrochloride NINGBO OCEAN CHEMICAL NEW MATE 2010-02-17 CN disclosed
EP-0479055-A1 Benzaldoximether derivatives BASF Aktiengesellschaft (DE) 1992-04-08 EP disclosed