Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GSK3A | P49840 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | STAT3 | P40763 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6688587 | 0.63 | HTT (0.33) | LMNAALDH1A1KDM4EPOLBMAPT | |
| Hydrochloric Acid SCHEMBL6439106 | 0.63 | HTT (0.33) | LMNAALDH1A1KDM4EPOLBMAPT | |
| Hydrochloric Acid SCHEMBL6444205 | 0.63 | HTT (0.33) | LMNAALDH1A1KDM4EPOLBMAPT | |
| SCHEMBL27910592 | 0.61 | — | — | |
| Bromide SCHEMBL2149556 | 0.60 | LMNA (0.37) | LMNAALDH1A1KMT2AKDM4EPOLB | |
| Hydrochloric Acid SCHEMBL2150060 | 0.60 | LMNA (0.37) | LMNAALDH1A1KMT2AKDM4EPOLB | |
| SCHEMBL27191543 | 0.60 | HSD17B10 (0.34) | LMNAALDH1A1KMT2AKDM4EPOLB | |
| Bromide SCHEMBL8941015 | 0.60 | — | — | |
| Bromide SCHEMBL27779447 | 0.59 | LMNA (0.36) | LMNAALDH1A1KMT2AKDM4EPOLB | |
| Hydrochloric Acid SCHEMBL27800771 | 0.59 | LMNA (0.36) | LMNAALDH1A1KMT2AKDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992020689-A1 | ANTIBACTERIAL PENEM DERIVATIVES | SMITHKLINE BEECHAM P.L.C. (GB) | 1992-11-26 | — | — | WO | disclosed |