Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9710262 | 0.91 | TSHR (0.39) | MAPTCYP3A4ALDH1A1TSHRTDP1 | |
| Propionic Acid SCHEMBL9710382 | 0.82 | COPS5 (0.36) | MAPTCYP3A4ALDH1A1TSHRTDP1 | |
| SCHEMBL9457572 | 0.72 | KDM4E (0.43) | MAPTCYP3A4ALDH1A1TSHRTDP1 | |
| SCHEMBL1250888 | 0.72 | MEN1 (0.37) | ALDH1A1TDP1MEN1KMT2AKDM4E | |
| SCHEMBL8771395 | 0.71 | ALDH1A1 (0.61) | MAPTCYP3A4ALDH1A1TSHRTDP1 | |
| SCHEMBL9457564 | 0.71 | KDM4E (0.40) | MAPTCYP3A4ALDH1A1TSHRTDP1 | |
| SCHEMBL111607 | 0.69 | GFER (0.62) | MAPTCYP3A4ALDH1A1TSHRMEN1 | |
| Hydrochloric Acid SCHEMBL2857384 | 0.67 | MAOB (0.61) | MAPTCYP3A4ALDH1A1MEN1RAB9A | |
| Iodide SCHEMBL31425562 | 0.67 | HTR2A (0.59) | MAPTCYP3A4ALDH1A1TSHRMEN1 | |
| SCHEMBL22701211 | 0.67 | CYP1A2 (0.36) | ALDH1A1TDP1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992021666-A1 | ANGIOTENSIN II RECEPTOR ANTAGONIST THIAZOLE DEVIVATIVES | LABORATOIRES UPSA (FR) | 1992-12-10 | — | — | WO | disclosed |