Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HRH2 | P25021 | 2/20 | 0.32 |
| ▸ | HRH1 | P35367 | 2/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.30 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16502343 | 0.82 | KDM4E (0.39) | CYP1A2KDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL7613003 | 0.78 | KDM4E (0.37) | CYP1A2KDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL12179151 | 0.78 | KDM4E (0.39) | CYP1A2KDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL9710262 | 0.76 | TSHR (0.39) | MEN1ALDH1A1LMNAKMT2AHRH3 | |
| SCHEMBL12866934 | 0.76 | KDM4E (0.35) | CYP1A2KDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL1250888 | 0.74 | MEN1 (0.37) | CYP1A2KDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL12881346 | 0.74 | ALDH1A1 (0.34) | CYP1A2KDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL3091821 | 0.74 | — | — | |
| Bromide SCHEMBL15757177 | 0.72 | ALDH1A1 (0.62) | CYP1A2KDM4EMEN1ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL7445751 | 0.72 | ALDH1A1 (0.62) | CYP1A2KDM4EMEN1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200369658-A1 | NOVEL COMPOUNDS | MISSION THERAPEUTICS LTD (GB) | 2020-11-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200369658-A1 | NOVEL COMPOUNDS | UCHL1, UCHL3, UCHL5 | CYP1A2 2383/4885KDM4E 178/4885MEN1 2215/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.