Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | COPS5 | Q92905 | 2/20 | 0.36 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.34 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.31 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.31 |
| ▸ | GLS | O94925 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9710262 | 0.91 | TSHR (0.39) | L3MBTL1LMNAALDH1A1CYP3A4TSHR | |
| Propionic Acid SCHEMBL9710300 | 0.83 | MAPT (0.43) | ALDH1A1TSHRMEN1MAPTRAB9A | |
| SCHEMBL9710327 | 0.82 | MAPT (0.37) | L3MBTL1LMNAALDH1A1CYP3A4TSHR | |
| SCHEMBL9458070 | 0.71 | AOC3 (0.45) | COPS5 | |
| SCHEMBL22701211 | 0.69 | CYP1A2 (0.36) | LMNAALDH1A1TDP1KDM4EMEN1 | |
| SCHEMBL28201814 | 0.69 | CYP3A4 (0.37) | COPS5L3MBTL1ALDH1A1CYP3A4TSHR | |
| Propionic Acid SCHEMBL27638989 | 0.68 | FFAR3 (0.56) | L3MBTL1LMNAALDH1A1CYP3A4TSHR | |
| SCHEMBL9457422 | 0.68 | COPS5 (0.44) | COPS5ALDH1A1CYP3A4TSHRTDP1 | |
| SCHEMBL9710192 | 0.68 | LDHA (0.37) | COPS5L3MBTL1LMNAALDH1A1TSHR | |
| SCHEMBL9458112 | 0.68 | AOC3 (0.58) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992021666-A1 | ANGIOTENSIN II RECEPTOR ANTAGONIST THIAZOLE DEVIVATIVES | LABORATOIRES UPSA (FR) | 1992-12-10 | — | — | WO | disclosed |